Kaley Cuoco is dripping mad sweat and running miles and miles into nowhere from her garage. The 35-year-old sitcom star was up early on Friday to clock in her treadmill times, posting for her 6.4 million Instagram followers and on a massive workout machine from her $12 million Hidden Hills estate. Putting the "Bang" into "Big Bang Theory," the blonde burned off every last calorie, and she admitted her spandex-clad sweat session was "no joke." Check out the killer workout below.